Protein Production & Characterization
Dr. Anja Schütz
Profile
Recombinantly produced proteins are used for a wide range of applications in life sciences. Our platform offers expertise and services for customized protein production. In addition, you can benefit from our knowledge in the biochemical and biophysical characterization of proteins.
Our mission is to enable technology development and cutting-edge research by fostering collaboration with other technology platforms and research groups. The PPC Platform offers customized protein production for various downstream applications such as:
- Interaction studies
- High-throughput screening campaigns
- Tool protein production
- Antigen/Antibody production
- Structural biology projects
- Biochemical & biophysical characterization
Next to customized protein production, the PPC Platform is an ideal partner to set up collaborative research projects on topics such as protein engineering and protein characterization. We have a strong interest in studying the structure-function relationship of proteins linked to human diseases. By applying various biochemical and biophysical methods, we delineate the physicochemical properties of the analyzed proteins, a prerequisite to understand their biological function.
The PPC Platform is in close contact with other protein productions sites and partakes in international benchmarking studies initiated through the P4EU network.
Besides being an established partner for educational training of MDC-internal apprentices, the PPC Platform is recruiting bachelor and master students. In the future, we want to promote the success of interdisciplinary PhD projects by offering the possibility of co-supervision of doctoral theses.
Are you interested in a collaboration with us? We are looking forward to your enquiry!
Team
Alumni
We thank our former team members for their active support.
Berger, Ingrid – Technical assistant
Donath, Mandy – Bachelor student
Haake, Fabian – Bachelor student
Lenski, Ulf – Bioinformatician
Kabuß, Loreen-Claudine H. – MDC apprentice
Kuhnke, Alina – MDC apprentice
Kurths, Silke – Technical assistant
Mustroph, Mandy – MDC apprentice
Radusheva, Veselina – Master student
Rossa, Denise – MDC apprentice
Simon, Carolin – Master student
Service & Technology
The PPCP laboratory has a strong technical expertise in the area of protein biochemistry.
We have established Standard Operating Procedures (SOPs) and attach particular importance to quality control. Our philosophy is to closely cooperate and actively exchange ideas with our collaborators, since this is essential for successful cooperation.
The following services are offered by the PPC platform:
| Consulting | Scientific & technical level |
|---|---|
Molecular biology services
| (1) Construct design (2) Gene cloning (3) Site-directed mutagenesis |
| Protein production services | (1) Small-scale expression & solubility screening (2) Scale-up expression (3) Protein purification |
| Protein characterization services | (1) Protein stability determination & optimization (2) Protein-ligand interaction studies (ligand = protein, nucleic acid, small molecule) (3) Oligomerization analysis (4) Protein intact mass analysis of peptides and proteins via LC/MS TOF (5) Protein structure determination (including crystallization, X-ray data collection) (6) Folding analysis |
In case you are interested in protein-related services not explicitly listed here, please contact us.
